
LET’S HACK THE CODE!
Just six decades after Orville and Wilbur Wright launched the aviation age, President Kennedy pronounced a moonshot: fly people to the moon and back. Eight years later, the mission was accomplished. Now, six decades after James Watson and Francis Crick discovered the code of life, it is time to embark on another historic mission: hack the code of life and cure aging.
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PALO ALTO PRIZE – TEAM APPROACH
There are two prizes available and teams may compete for one or both prizes:
• A $500,000 Longevity Demonstration Prize will be awarded to the first Team that meets all the requirements of the Prize Requirements as determined by the Judging Panel in its sole discretion, including extending the mean lifespan of a wild-type mammalian intervention cohort by 50% relative to acceptable published natural history of untreated norms in a statistically significant (p<.05) manner, using a Statistical Model (as defined and approved in the official “Competition Agreement”). The intervention and control cohorts should be age and gender matched and should include an equal number of males and females. If you would like more details on the Prize Requirements please use the contact form at the bottom of this page.
Each team participating in the Prize is responsible for funding 100% of its participation in the Prize including all research and development costs and publishing its work and/or the reproduction of results. To enable a rapid commercial path forward for the innovations, the sponsor of the Prize will be contributing an existing pool of relevant intellectual property to the Prize effort.
PALO ALTO PRIZE – PERSONAL STORIES
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WHY A PRIZE?
Incentive prizes work because they attract:

Minds
Prizes attract the best minds to focus on finding solutions to a specific area of innovation. From researchers at universities, to startups, to small teams within larger companies, prizes create a target for innovators to try to solve. Prize purses, advanced market commitments, and the glory of winning helps “pull” innovation in a specific direction. By creating a new playing field, prizes also help pull everyone together toward the common goal.

Media
Everyone loves a competition and everyone loves heroes, especially the media! When crafted and produced well, incentive prizes are a great way to tell stories and to educate the public about the area of discovery. They also provide a wonderful medium to create heroes out of the hard-working teams that make it happen.

Money
Once you have the best minds in the world focusing on a breakthrough area, capital will follow. Angel investors, venture capital funds, and the venture arms of corporations are always looking for the next breakthrough area and teams to invest in. Prizes help unearth who those teams are, and what they are working on related to the prize, and other products, services and intellectual property that they might have that are not related to the prize.

ADVISORY BOARD

VICTOR DZAU, M.D.
President of the Institute of Medicine

LEONARD GUARENTE, Ph.D.
Director, Glenn Laboratory for the Science of Aging at MIT

Dr. STUART KIM, Ph.D
Professor, Depts. of Developmental Biology and Genetics
Stanford University Medical Center

DAVID SINCLAIR, Ph.D.
Professor, Genetics Dept. Harvard Medical School

JOHN SEDIVY Ph.D.
Brown Faculty, Department of Molecular Biology, Cell Biology, and Biochemistry

KEITH BLACKWELL, M.D, Ph.D.
Principal Investigator, The Blackwell Lab at the Joslin Diabetes Center

SUSAN PESCHIN
President and CEO
Alliance for Aging Research

RUSSEL J. REITER, Ph.D., Dr.H.C.MULT.
Professor of Cell Biology, UT Health Science Center

STEVE JURVETSON
Managing Director, Draper Fisher Jurvetson

JACK HIDARY
Founder, Hidary Foundation

FRANK LONGO, M.D.
Professor and Chair, Department of Neurology and Neurological Sciences, Stanford University

CHARLES CHO, M.D.
Professor of Neurology and Neurosurgery, Stanford University

ERIC VERDIN, M.D.
Senior Investigator, Gladstone Institute of Virology and Immunology Professor, UCSF School of Medicine

KEVIN PERROTT
Executive Director – Mprize, Methuselah Foundation

SONIA ARRISON
Author, 100 Plus

KEITH POWERS
President, Engaged Partners (Frm. EVP of Strategy, X PRIZE Foundation)

GUY P. NOHRA
Co-Founder and Managing Director, Alta Partners

REESE JONES
Associate Founder, Singularity University; Trustee, Santa Fe Institute

FEDERICK J. DOTZLER
Managing Director, De Novo Ventures

NINA KJELLSON
Managing Director, Interwest Ventures

LAURA DEMING
Founder, Longevity Fund

STEVE HERROD
Managing Director, General Catalyst Partners

STEVE VASSALLO
General Partner, Foundation Capital

CAMI SAMUELS
Managing Director, Versant Ventures

GARHENG KONG, M.D., MBA
Managing General Partner, Sofinova Ventures

PATRICK ENRIGHT
Founder and Managing Director, Longitude Capital

JIM GLASHEEN, PH.D.
General Partner, Technology Partners

ROGER J. QUY, PH.D.
General Partner, Technology Partners

KEVIN STARR
Partner, Third Rock Ventures Patrick-Enright

JOSH MAKOWER, M.D.
Founder and CEO, ExploraMed

KERRY DOLAN
Assistant Managing Editor, Forbes

AMIR RUBIN
President and CEO of Stanford Hospital & Clinic

BARBARA J. NATTERSON-HOROWITZ, M.D.
Professor of Medicine, UCLA Division of Cardiology

DAN MOORE
President and CEO, Cyberonics, Inc.

GRAHAM SPENCER
General Partner, Google Ventures, Trustee, Santa Fe Institute

BOB HARRINGTON, M.D.
Chairman, Department of Medicine, Stanford University

DAVID ARRINGTON
Associate Vice Chancellor, University Relations, UC San Francisco

AUBREY DE GREY, MA, PH.D
Ph.D, Chief Science Officer, SENS Foundation

VALTER LONGO, PH.D.
Director, USC Longevity Institute

JEAN-JACQUES BIENAIME
CEO, Biomarin

BEN BARRES, M.D., PH.D.
Chairman, Department of Neurobiology, Stanford University

FRANK FISCHER
President and CEO, Neuropace, Inc.

JAMES R. DOTY, M.D.
Professor of Neurosurgery, Stanford University Founder and Director of CCARE

ALAN GREENE, MD
Author, Pediatrician, Founding President of the Society of Participatory Medicine

BRIAN KENNEDY,PH.D.
CEO and President, The Buck Institute for Research on Aging

LEIGHTON READ, M.D.
Venture Partner, Alloy Ventures

HOYOUNG HUH
Managing Director, Konus Advisory Group

ALBERT CHA
Managing Partner, Vivo Ventures

MICHAEL MCCULLOUGH, M.D.
Principal, Capricorn Healthcare & Special Opportunities

JENNIFER ALDEN
Director, Digital Content Strategy, Palo Alto Investors

CASPER deCLERQ
Partner, Norwest Venture Partners

CHARLES WARDEN
Managing Director, Versant Ventures

OLEG NODELMAN
Managing Partner, EcoR1 Capital

STACEY CHANG
Director, Healthcare Practice at IDEO

WAYNE B. JONAS, M.D.
President & CEO Samueli Institute

CONRAD YUN
Yun Family Enterprises & Palo Alto Institute
ABOUT US
The Palo Alto Prize is a newly established Silicon Valley-based initiative of the Race Against Time Foundation. The mission of the Palo Alto Prize is to encourage collaboration, foster innovation, and build a community to address the underlying causes of aging. In addition to the $1 million of cash prizes, the Palo Alto Prize is also working with a number of angel investors, venture capital firms, corporate venture arms, institutions and private foundations to provide access to additional capital to the teams during the competition. While the Palo Alto Prize will help facilitate introductions, all transactions and due diligence will be done privately between the teams and potential investors and philanthropists.
The Race Against Time (dba The Hero Science Foundation www.herosf.org) is a 501(c)(3) educational non-profit organization (Tax ID: 47-2823482) created to raise public awareness and financial support for basic biomedical research related to increasing our health span and defining the fundamental biological mechanisms that prevent age-related diseases and disabilities.
About the prize sponsor:
Dr. Joon Yun, M.D., is the President of Palo Alto Investors, LLC, founded in 1989 with over $2 billion in assets under management invested in healthcare and the founder of the Palo Alto Institute, a nonprofit think-tank that has been providing operational support for the Palo Alto Prize. Board certified in radiology, Dr. Yun served on the clinical staff at Stanford Hospital from 2000-2006. Dr. Yun received his Bachelor of Arts in biology from Harvard University and his Doctor of Medicine from Duke University School of Medicine. Learn more at DrJoonYun.com and follow him at @drjoonyun