PALTHON

Team Name:

PALTHON

Team Leader Name:

Douglas E Vaughan, M.D.

Location

Chicago, IL

Approach:

PAI-1 Signaling

Affiliation:

Northwestern University, Feinberg School of Medicine

Link:

http://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=17998

Team Leader Bio:

Navtej Toor, Ph.D. is an Assistant Professor of Chemistry and Biochemistry at UC San Diego. The projects in his lab focus on the structure and function of non-coding regions of prokaryotic and eukaryotic genomes. Two genetic elements particularly abundant in these organisms are introns and retroelements, which comprise ~50% of the human genome. Previously, he worked to determine the first crystal structure of a group II intron. Group II introns are thought to be the ancestors of all the introns and retroelements found in higher organisms. Due to this evolutionary relationship, the crystal structure revealed the catalytic mechanism behind RNA splicing in eukaryotes.

Email Contact for Team

ntoor@ucsd.edu
858-534-3211
Assistant Professor
UC San Diego, 92131